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It has been observed that koi with a heavy infestation increase their flashing when Prazi is first used. It is speculated that the flukes get active due to the action of the Prazi on them. After a day or two the flashing subsides. ... you may also observe larger intestinal worms on the floor of the pond after 24-48 hours.
Whether this is what is occurring in your situation, I cannot say.
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