| Mark Cooper, Q. Take the hypothetical example of a Koi dealer who uses antibiotics prophylactically, and a hobbyist purchases a Koi from said dealer, probably being unaware that it has been treated with antibiotics. Then as part of that hobbyist’s QT protocol it goes through another prophylactic course of antibiotics. Is that good for the Koi ? Does it increase the risk of antibiotic resistance ? A. When koi are given drugs, the quantity of residual drugs remaining in the body varies depending on the rate the drugs are absorbed and excreted. In general, the larger the quantity of drugs given, the more residual drugs will remain in the body. However, when comparing different drugs, the residual amount is determined by the amount absorbed and the amount excreted, which depend on the physical characteristics of the drug. A drug to drug reaction will occur if sufficient quantities of both drugs are present in the body. Some combinations could be synergistic in nature, others toxic and some with no effect. Imagine all the stratas of the koi industry… from breeder, jobber, dealer, hobbyist/collector. A pathogen could originate at any strata but requires wide distribution to make an impact. Imagine a how a mutated bacterium could geometrically spread through a jobber’s facility and finally end up in your pond. An upward migration is not going to take place, or unlikely at the very least. I think there is very little risk at the hobbyist level to create the next super pathogen. If it does occur, the isolated bacterium has a reasonable chance to revert to normal over time. I’m hearing many accounts of parasites that are developing resistances to conventional treatments. This has got to be occurring at the breeders level, because of ineffective applications of treatments. One has to weigh all the risks, perceived and unperceived, and take on the personal responsibility to protect ones investment and safe guard the long term health and well being of your koi.
Regards,
Mark |