
Bud, if you count the series of three shots per fish as separate events, I have conservatively treated , over the past 18 years or so, 5,000 koi with this technique. And you sir are INCORRECT!
You don't debride margins of an ulcer mechanically like preparing to suturing a wound that has been open for a while. All ulcers can be described as wounds, but not all wounds are ulcers! Our 'foot friend Brutus can tell you about diabetes ulcers on the foot and their healing verse an injury that results on a foot. Ulcers are a site of infection, pure and simple.
The ulcer itself, is a decay of the epidermal and dermal layer. The dermal layer is damaged by toxic byproduct from aeromonas metabolic activity. And the bacteria and it's agents are IN the cell tissue. Only secondary invaders like pseudomonas, for instance, are setting up and limited to/ on the surface itself. In other words, there is healthy tissue, very necrotic tissue and dying tissue, as well as superficial and embedded bacteria count. Sooooooo an antisceptic for cleaning surface bacteria or even a heaby handed burn is not enough. You need physical effort to remove suspect cells.
I repeat, Betadine, applied one or two two times ( if needed and a physical contact and removal of dead and decaying flesh is needed before healthy tissue can begin to skin over.
If the fish is responsive and if you have provided a steroid locally to reduce swelling from antisceptic and reaction to infection and if you have kept bacteria very low from topical antibiotic coverage as well as provided antibiotoc blood levels via injection ( that rise from below the infected area and treat from the 'inside out'---- you will have the beginning of white skinning of the ulcer at temperature ( 70 F- 80 F) within three- five days.
Trust me on this ( I've seen it 5000 times!)

JR